Understanding hypermobile Ehlers-Danlos, & hypermobility spectrum disorder - This week, we're looking at features of the skin in hEDS. Manifestations that can arise include stretch marks, piezogenic papules, hyperextensibility, and atrophic scarring.
![Frontiers | Case report: Mild phenotype of a patient with vascular Ehlers–Danlos syndrome and COL3A1 duplication mutation without alteration in the [Gly-X-Y] repeat sequence Frontiers | Case report: Mild phenotype of a patient with vascular Ehlers–Danlos syndrome and COL3A1 duplication mutation without alteration in the [Gly-X-Y] repeat sequence](https://www.frontiersin.org/files/Articles/1017446/fgene-13-1017446-HTML-r1/image_m/fgene-13-1017446-g001.jpg)
Frontiers | Case report: Mild phenotype of a patient with vascular Ehlers–Danlos syndrome and COL3A1 duplication mutation without alteration in the [Gly-X-Y] repeat sequence
![Ehlers-Danlos Syndrome Related to Gastrointestinal Problems and Eating Disorders - Universitat Autònoma de Barcelona - UAB Barcelona Ehlers-Danlos Syndrome Related to Gastrointestinal Problems and Eating Disorders - Universitat Autònoma de Barcelona - UAB Barcelona](http://www.uab.cat/Imatge/466/639/sindrome-ehlers-danlos-wide-web.jpeg)
Ehlers-Danlos Syndrome Related to Gastrointestinal Problems and Eating Disorders - Universitat Autònoma de Barcelona - UAB Barcelona
![Bendy joints, stretchy skin, clumsiness. Why hypermobile Ehlers-Danlos Syndrome is often missed – and what it has to do with autism Bendy joints, stretchy skin, clumsiness. Why hypermobile Ehlers-Danlos Syndrome is often missed – and what it has to do with autism](https://images.theconversation.com/files/516291/original/file-20230320-15-zym4lc.jpg?ixlib=rb-1.1.0&rect=70%2C20%2C6639%2C4446&q=20&auto=format&w=320&fit=clip&dpr=2&usm=12&cs=strip)
Bendy joints, stretchy skin, clumsiness. Why hypermobile Ehlers-Danlos Syndrome is often missed – and what it has to do with autism
![A floppy infant without lingual frenulum and kyphoscoliosis: Ehlers Danlos syndrome case report | Italian Journal of Pediatrics | Full Text A floppy infant without lingual frenulum and kyphoscoliosis: Ehlers Danlos syndrome case report | Italian Journal of Pediatrics | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13052-021-00984-y/MediaObjects/13052_2021_984_Fig1_HTML.png)
A floppy infant without lingual frenulum and kyphoscoliosis: Ehlers Danlos syndrome case report | Italian Journal of Pediatrics | Full Text
![Skin Manifestations, Multiple Aneurysms, and Carotid-Cavernous Fistula in Ehlers-Danlos Syndrome Type IV | Circulation Skin Manifestations, Multiple Aneurysms, and Carotid-Cavernous Fistula in Ehlers-Danlos Syndrome Type IV | Circulation](https://www.ahajournals.org/cms/asset/1fe9e149-0b1b-414e-bda9-4ca3e438fb3c/hc3893088001.jpeg)
Skin Manifestations, Multiple Aneurysms, and Carotid-Cavernous Fistula in Ehlers-Danlos Syndrome Type IV | Circulation
![Examples of cutaneous and articular manifestations of Ehlers-Danlos... | Download Scientific Diagram Examples of cutaneous and articular manifestations of Ehlers-Danlos... | Download Scientific Diagram](https://www.researchgate.net/publication/271596334/figure/fig1/AS:295135511367701@1447377197863/Examples-of-cutaneous-and-articular-manifestations-of-Ehlers-Danlos-syndrome-EDS.png)
Examples of cutaneous and articular manifestations of Ehlers-Danlos... | Download Scientific Diagram
![a, b) An 8-year-old girl with Ehlers-Danlos syndrome showing marked... | Download Scientific Diagram a, b) An 8-year-old girl with Ehlers-Danlos syndrome showing marked... | Download Scientific Diagram](https://www.researchgate.net/publication/318166925/figure/fig5/AS:738236972408833@1553020818163/a-b-An-8-year-old-girl-with-Ehlers-Danlos-syndrome-showing-marked-scarring-of-the-skin.jpg)
a, b) An 8-year-old girl with Ehlers-Danlos syndrome showing marked... | Download Scientific Diagram
This week, we're looking at skin in hEDS. Manifestations that can arise include piezogenic papules, stretch marks, mild hyperextensibility, unusually soft/doughy/smooth skin texture and atrophic scarring. Slow wound healing, easy bruising (to
![Pediatric Dermatology : Ehlers Danlos Syndrome : Ehlers Danlos Syndrome Patient Education : Diseases and Conditions | Pediatric Oncall Pediatric Dermatology : Ehlers Danlos Syndrome : Ehlers Danlos Syndrome Patient Education : Diseases and Conditions | Pediatric Oncall](https://www.pediatriconcall.com/master/bucket-img/130-ehlers-danlos-syndrome/ehlers-danlos-syndrome-1.jpg)
Pediatric Dermatology : Ehlers Danlos Syndrome : Ehlers Danlos Syndrome Patient Education : Diseases and Conditions | Pediatric Oncall
![Clinical and molecular characterization of 40 patients with classic Ehlers–Danlos syndrome: identification of 18 COL5A1 and 2 COL5A2 novel mutations | Orphanet Journal of Rare Diseases | Full Text Clinical and molecular characterization of 40 patients with classic Ehlers–Danlos syndrome: identification of 18 COL5A1 and 2 COL5A2 novel mutations | Orphanet Journal of Rare Diseases | Full Text](https://media.springernature.com/full/springer-static/image/art%3A10.1186%2F1750-1172-8-58/MediaObjects/13023_2013_Article_564_Fig2_HTML.jpg)
Clinical and molecular characterization of 40 patients with classic Ehlers–Danlos syndrome: identification of 18 COL5A1 and 2 COL5A2 novel mutations | Orphanet Journal of Rare Diseases | Full Text
![Hypermobile Ehlers–Danlos syndrome (a.k.a. Ehlers–Danlos syndrome Type III and Ehlers–Danlos syndrome hypermobility type): Clinical description and natural history - Tinkle - 2017 - American Journal of Medical Genetics Part C: Seminars in Hypermobile Ehlers–Danlos syndrome (a.k.a. Ehlers–Danlos syndrome Type III and Ehlers–Danlos syndrome hypermobility type): Clinical description and natural history - Tinkle - 2017 - American Journal of Medical Genetics Part C: Seminars in](https://onlinelibrary.wiley.com/cms/asset/e2e81823-ed44-45c6-be03-3cf436bf1e7b/ajmg.c.v175.1.cover.jpg)
Hypermobile Ehlers–Danlos syndrome (a.k.a. Ehlers–Danlos syndrome Type III and Ehlers–Danlos syndrome hypermobility type): Clinical description and natural history - Tinkle - 2017 - American Journal of Medical Genetics Part C: Seminars in
![The role of cutaneous manifestations in the diagnosis of the Ehlers‐Danlos syndromes - Stembridge - 2023 - Skin Health and Disease - Wiley Online Library The role of cutaneous manifestations in the diagnosis of the Ehlers‐Danlos syndromes - Stembridge - 2023 - Skin Health and Disease - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/2ac7ce6d-e86f-43a3-901a-041e3f56ac1e/ski2140-fig-0001-m.jpg)